PRO-glio is a Norwegian/Swedish study. It investigates whether radiation with protons or photons is more effective for IDH-mutated diffuse gliomas in grades II and III.

Malin Blomstrand is a senior physician at Sahlgrenska University Hospital in Gothenburg and leads the study in Sweden.

"We will examine patients who have received proton and photon radiation to see if there is any difference in cognitive abilities, such as memory and learning. We will also study the occurrence of extreme fatigue, known as fatigue. Our hope is that the results will show when one treatment method is preferable," she said in a statement on the Skandion Clinic's website.

Unlike traditional X-ray and electron radiation, which pass straight through the body and therefore also damage healthy tissue, the energy of a proton beam can be adjusted to reach a specific depth. In this way, the radiation can be concentrated on the tumor itself, and the radiation dose can be increased without increasing the risk of side effects. Photon therapy is a high-energy X-ray radiation that works in a similar way.

More information about PRO-glio

Cancercentrum.se: PRO-glio

Skandionkliniken.se